Elif Karagöz

BSc in Molecular Biology and Genetics 2004, Middle East Technical University; MSc in Molecular Biology,
2006, Max Planck Research School Göttingen; PhD in Chemistry, Utrecht University; postdoc University of California at San Francisco

Elif Karagöz is a Group Leader at Max Perutz Laboratories and the Medical University of Vienna (MUW). Karagöz lab works towards revealing how cells sense and respond to the perturbations to protein folding homeostasis at the mechanistic level. To this end, they combine cell biology, in vitro reconstitution, and structural biology (NMR spectroscopy) to dissect these processes from cellular to atomic level. Karagöz lab currently focuses on understanding how cells sense protein folding stress in the ER by reconstituting the interplay among chaperones, unfolded polypeptides with the conserved ER-tethered stress sensors. In parallel, they study the posttranscriptional mechanisms that regulate protein synthesis to adjust ER protein-folding capacity during ER stress. Elif Karagöz is currently supervising 2 PhD students and a Master Student in her own lab and has contributed to the supervision of 5 PhD students and many interns and rotation students during her postdoctoral training. For her work, she received the best PhD Award at Bijvoet Graduate School, Utrecht University.